HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Acetate → 1-[3-(6-(Furan-3-yl)-3H-imidazo[4.5-b]pyridin-3-yl)phenyl]pyrrolidin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | 1-[3-(6-Bromo-3H-imidazo[4,5-b]pyridin-3-yl)phenyl]pyrrolidin-2-one | HCID 22727958 | — |
| Product | 1-[3-(6-(Furan-3-yl)-3H-imidazo[4.5-b]pyridin-3-yl)phenyl]pyrrolidin-2-one | HCID 9798208 | — |
Reaction Steps
The title compound was prepared from 1-[3-(6-bromo-3H-imidazo[4,5-b]pyridin-3-yl)phenyl]pyrrolidin-2-one as described in Example 1. Free base, yellow crystals, m.p. 208-210° C. (from ethyl acetate); δH (360 MHz, d6-DMSO) 2.11 (2H, quin, J 7), 2.54 (2H, t, J 8), 3.93 (2H, t, J 7), 7.16 (1H, s), 7.60 (1H, t, J 8), 7.68-7.71 (1H, m), 7.78-7.81 (2H, m), 8.28 (1H, t, J 2), 8.35 (1H, s), 8.48 (1H, s), 8.76 (1H, s), 8.90 (1H, s); m/z (ES+) 345 (M++H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06723735B1 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-e8ded4083efd4f0aadcfd6839530be1c |
| Source note | uspto-grants-2004_04 |