Ethanol → HCID 22727954, compound

HRID 2086076Notes

Reaction equation

HRID 2086076 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]([N+:20]([O-])=O)[C:5]([NH:8][C:9]2[CH:14]=[CH:13][CH:12]=[C:11]([N:15]3[CH:19]=[CH:18][N:17]=[CH:16]3)[CH:10]=2)=[N:6][CH:7]=1.[CH2:23](O)C>>[Br:1][C:2]1[CH:3]=[C:4]2[N:20]=[CH:23][N:8]([C:9]3[CH:14]=[CH:13][CH:12]=[C:11]([N:15]4[CH:19]=[CH:18][N:17]=[CH:16]4)[CH:10]=3)[C:5]2=[N:6][CH:7]=1

Participants

3

Reactant 2

HCID 702EthanolHCID 22727955HCID 22727955, compound

Product 1

HCID 22727954HCID 22727954, compound

Procedure

6-Bromo-3-[3-(imidazol-1-yl)phenyl]-3H-imidazo[4,5-b]pyridine was prepared from N-(5-bromo-3-nitropyridin-2-yl)-N-[3-(imidazol-1-yl)phenyl]amine as described in Example 1. Oxalate salt, cream-coloured powder, m.p. 236-238° C. (from ethanol); δH (400 MHz, d6-DMSO) 7.23 (1H, s), 7.75 (2H, m), 7.92 (1H, s), 8.01-8.03 (1H, m), 8.24 (1H, s), 8.51 (1H, s), 8.57 (2H, dd, J 6 and 2), 9.09 (1H, s); m/z (ES+) 340 and 342 (M++H).

Sources & evidence

ORD record
ord-200edbd171464a53af0188e68c32844b
Source dataset
uspto-grants-2004_04
Patent number
US06723735B1

Reaction notes

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