3-(Morpholin-4-ylmethyl)aniline → HCID 22727949, compound
Reaction equation
[Br:1][C:2]1[CH:3]=[C:4]([N+:9]([O-:11])=[O:10])[C:5](Cl)=[N:6][CH:7]=1.[N:12]1([CH2:18][C:19]2[CH:20]=[C:21]([NH2:25])[CH:22]=[CH:23][CH:24]=2)[CH2:17][CH2:16][O:15][CH2:14][CH2:13]1>>[Br:1][C:2]1[CH:3]=[C:4]([N+:9]([O-:11])=[O:10])[C:5]([NH:25][C:21]2[CH:22]=[CH:23][CH:24]=[C:19]([CH2:18][N:12]3[CH2:13][CH2:14][O:15][CH2:16][CH2:17]3)[CH:20]=2)=[N:6][CH:7]=1Participants
3
Procedure
N-(5-Bromo-3-nitropyridin-2-yl)-N-[3-(morpholin-4-ylmethyl)phenyl]amine was prepared from 5-bromo-2-chloro-3-nitropyridine and 3-(morpholin-4-ylmethyl)phenylamine as described in Example 3.
Sources & evidence
- ORD record
- ord-f7b90f078f614817982e499a95fdaabc
- Source dataset
- uspto-grants-2004_04
- Patent number
- US06723735B1
Reaction notes
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