HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methoxyethylamine → 2-[3,5-Bis(2-hydroxyphenyl)-[1,2,4]triazol-1-yl]-N-(2-methoxyethyl)acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methoxyethylamine | HCID 8018 | — |
| Reactant | Ethyl [3,5bis(2-hydroxyphenyl)-[1,2,4]triazol-1-yl]acetate | HCID 135914986 | — |
| Product | 2-[3,5-Bis(2-hydroxyphenyl)-[1,2,4]triazol-1-yl]-N-(2-methoxyethyl)acetamide | HCID 135817491 | — |
Reaction Steps
4.0 g of ethyl [3,5-bis(2-hydroxyphenyl)-[1,2,4]triazol-1-yl]acetate (Example 2) are dissolved in 30 ml of 2-methoxyethylamine and the mixture is stirred at room temperature for 2 h. It is concentrated to dryness in vacuo and the residue is crystallized from isopropanol. After drying, 2-[3,5-Bis(2-hydroxyphenyl)-[1,2,4]triazol-1-yl]-N-(2-methoxyethyl)acetamide remains as colorless crystals of m.p. 184-186° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06723742B2 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-b81518afc71947aa9d73c332888ee5d6 |
| Source note | uspto-grants-2004_04 |