1-Naphthol → HCID 12125309, compound

Participants

Reaction Steps

The title compound was prepared by reacting 1-naphthol (5.7 g, 39.6 mmol) with 5-methoxy-2-bromobenzyl alcohol as described for intermediate 5 to yield 5.94 g (44%) of a white solid: mp 74-75° C.; 1H NMR (CDCl3): δ 3.78 (3H, s), 5.28 (2H, s), 6.77 (1H, dd, J=2.93 Hz, J=8.79 Hz), 6.88 (1H, d, J=7.69 Hz), 7.27 (1H, d, J=3.30 Hz), 7.36-7.39 (1H, m), 7.47-7.53 (4H, m), 7.81-7.83 (1H, m), 8.37-8.39 (1H, m); MS (ESI) m/z 343/345 ([M+H]+);

Provenance & Evidence