Potassium tert-butoxide → HCID 69545678, compound

Participants

Reaction Conditions

Reaction Steps

A solution of methyl 4-[[2-(N′-tert-butoxycarbonylhydrazino)-2-oxoethyl](6-chloro-naphthalene-2-sulfonyl)amino]-2-butenoate (500 mg) in THF (25 ml) was combined with potassium t-butoxide (22 mg) and stirred at 70° C. for 15 hours. The reaction mixture was concentrated and the residue was dissolved in ethyl acetate, washed with water and brine, dried and concentrated to obtain the title compound (500 mg) as a colorless amorphous material.

Provenance & Evidence