HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methoxyacetic Acid → 4-(6-Chloronaphthalene-2-sulfonyl)-1-{(2-methoxyethyl)[1-(4-pyridyl)-4-piperidinyl]amino}-2-piperazinone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methoxyacetic Acid | HCID 12251 | — |
| Reactant | 4-(6-Chloronaphthalene-2-sulfonyl)-1-[1-(4-pyridyl)-4-piperidinylamino]-2-piperazinone | HCID 17825410 | — |
| Product | 4-(6-Chloronaphthalene-2-sulfonyl)-1-{(2-methoxyethyl)[1-(4-pyridyl)-4-piperidinyl]amino}-2-piperazinone | HCID 22727259 | — |
Reaction Steps
Similarly to Method B in Example 43 and using 4-(6-chloronaphthalene-2-sulfonyl)-1-[1-(4-pyridyl)-4-piperidinylamino}-2-piperazinone (200 mg) and methoxyacetic acid (4 ml) instead of acetic acid, the title compound (123 mg) was obtained as colorless crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06723722B1 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-bd220f367a9f40729b21aaf79fb8c662 |
| Source note | uspto-grants-2004_04 |