HuagongsheHuagongshe Chemistry Print Report · For research reference only
7-chloronaphthalene-2-sulfonyl Chloride → (3S)-3-(7-Chloronaphthalene-2-sulfonylamino)-1-[1-(4-pyridyl)-4-piperidinylamino}-2-pyrrolidone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 7-chloronaphthalene-2-sulfonyl Chloride | HCID 10563334 | — |
| Reactant | HCID 69545831 | HCID 69545831 | — |
| Product | (3S)-3-(7-Chloronaphthalene-2-sulfonylamino)-1-[1-(4-pyridyl)-4-piperidinylamino}-2-pyrrolidone | HCID 69546113 | 30% |
Reaction Steps
Similarly to Example 86 and using (3S)-3-(tert-butoxycarbonylamino)-1-[1-(4-pyridyl)-4-piperidinylamino]-2-pyrrolidone (220 mg) and 7-chlornaphthalene-2-sulfonyl chloride (170 mg), the title compound (88 mg) was obtained as colorless crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06723722B1 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-72dd2a0114d14e618513453c0f610eb7 |
| Source note | uspto-grants-2004_04 |