HuagongsheHuagongshe Chemistry Print Report · For research reference only
N,N-Dimethylethylenediamine → 4-[(6-Chloro-2-naphthyl)sulfonyl]-N-[2-(dimethylamino)ethyl]-1-[methyl[1-(4-pyridinyl)-4-piperidinyl]amino]-6-oxo-2-piperazinecarboxamide Dihydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N,N-Dimethylethylenediamine | HCID 66053 | — |
| Reactant | 4-[(6-Chloro-2-naphthyl)sulfonyl)-1-[methyl[1-(4-pyridinyl)-4-piperidinyl]amino]-6-oxo-2-piperazinecarboxylic Acid | HCID 22727237 | — |
| Product | 4-[(6-Chloro-2-naphthyl)sulfonyl]-N-[2-(dimethylamino)ethyl]-1-[methyl[1-(4-pyridinyl)-4-piperidinyl]amino]-6-oxo-2-piperazinecarboxamide Dihydrochloride | HCID 22727056 | — |
Reaction Steps
Similarly to Example 116 and using 4-[(6-chloro-2-naphthyl)sulfonyl)-1-[methyl[1-(4-pyridinyl)-4-piperidinyl]amino]-6-oxo-2-piperazinecarboxylic acid (0.18 g) obtained in Example 110 and N,N-dimethyl ethylenediamine (0.035 ml), the title compound (0.17 g) was obtained as a pale yellow powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06723722B1 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-1c2b5776475a44beab75c1b61252de02 |
| Source note | uspto-grants-2004_04 |