Diethyl Ether → HCID 22727321, compound

Participants

Reaction Steps

3-[3-(3-nitrophenyl)isoxazol-5-yl]propan-1-ol (1.02 g, 4.1 mmol), sodium acetate (0.10 g, 1.3 mmol), and pyridinium chlorochromate (1.77 g, 8.2 mmol) were added in 30 mL of dry methylene chloride. After the reaction was continued for 4 hr at an ambient temperature, diethyl ether was added and the reaction mixture was filtered through a cellite bed. 0.6 g (64%) of the target compound was obtained by removing all the solvent and purifying by column chromatography on silica gel.

Provenance & Evidence