HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Phenylpiperazine → HCID 10132780, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Phenylpiperazine | HCID 7096 | — |
| Reactant | Sodium triacetoxyborohydride | HCID 5049666 | — |
| Reactant | HCID 22727325 | HCID 22727325 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 10132780 | HCID 10132780 | 77.4% |
Reaction Steps
About 2 min after dissolving 3-[3-(2-thienyl)isoxazol-5-yl]propanal (20 mg, 0.1 mmol), 1-phenylpiperazine (14.7, 0.1 mmol) in 2 mL of dry methylene chloride, were added NaBH(OAc)3 (61.4 mg, 0.3 mmol) and molecular sieves (5 beads). The reaction mixture was reacted for 3.5 hr and followed the same processes as in Example 1 to obtain 26.4 mg (77.4%) of the target compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06723724B2 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-6b81922bdf3248fabfb0d64324b860e7 |
| Source note | uspto-grants-2004_04 |