HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Phenylpiperazine → HCID 10225222, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Phenylpiperazine | HCID 7096 | — |
| Reactant | Sodium triacetoxyborohydride | HCID 5049666 | — |
| Reactant | HCID 22727349 | HCID 22727349 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 10225222 | HCID 10225222 | 127.4% |
Reaction Steps
About 2 min after dissolving 3-[3-(3-phenoxyphenyl)isoxazol-5-yl]propanal (20 mg, 0.07 mmol) and 1-phenylpiperazine (10.4, 0.07 mmol) in 2 mL of dry methylene chloride, were added NaBH(OAc)3 (43.4 mg, 0.2 mmol) and molecular sieves (5 beads). The reaction mixture was reacted for 16 hr and followed the same processes as in Example 1 to obtain 39.2 mg (100%) of the target compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06723724B2 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-b33cf8a446714012adf7b3cc3381d99e |
| Source note | uspto-grants-2004_04 |