HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Benzylpiperazine → HCID 69891077, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Benzylpiperazine | HCID 75994 | — |
| Reactant | Sodium triacetoxyborohydride | HCID 5049666 | — |
| Reactant | HCID 73993903 | HCID 73993903 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 69891077 | HCID 69891077 | 68.4% |
Reaction Steps
About 2 min after dissolving 3-[3-(2-phenylvinyl)isoxazol-5-yl]propanal (10 mg, 0.04 mmol) and 1-benylpiperazine (7.6, 0.04 mmol) in 2 mL of dry methylene chloride, were added NaBH(OAc)3 (28 mg, 0.13 mmol) and molecular sieves (5 beads). The reaction mixture was reacted for 16.4 hr and followed the same processes as in Example 1 to obtain 10.6 mg (62.2%) of the target compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06723724B2 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-46f0569f2da9400680bfcb098dad27ae |
| Source note | uspto-grants-2004_04 |