Aluminium lithium hydride → HCID 178484821, compound

HRID 2086559Notes

Reaction equation

HRID 2086559 reaction equation
C(O[C:9](=O)[NH:10][C@H:11]1[CH2:16][CH2:15][C@@H:14]([F:17])[CH2:13][CH2:12]1)C1C=CC=CC=1.[H-].[Al+3].[Li+].[H-].[H-].[H-]>>[F:17][C@@H:14]1[CH2:15][CH2:16][C@H:11]([NH:10][CH3:9])[CH2:12][CH2:13]1

Participants

3

Reactant 2

HCID 21226445Aluminium lithium hydrideHCID 178523784HCID 178523784, compound

Product 1

HCID 178484821HCID 178484821, compoundYield 91%

Procedure

The title compound was prepared from (cis)-(4-fluoro-cyclohexyl)-carbamic acid benzyl ester by lithium aluminum hydride reduction under standard conditions in 91% yield.

Sources & evidence

ORD record
ord-ea73b0478d5447818e06b6141fdc2255
Source dataset
uspto-grants-2004_04
Patent number
US06727247B2

Reaction notes

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