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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2086568Generated: October 25, 2026

Triethylamine → 5-phenyl-penta-2,4-dienoic acid-N-(2-carboxy-4-fluoro-phenyl)-amide

https://huagongshe.com/reaction/2086568

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTriethylamineHCID 8471—
Reactant2-Amino-5-fluorobenzoic acidHCID 101412—
Reactant2,4-Pentadienoyl chloride, 5-phenyl-HCID 3084809—
SolventTetrahydrofuranHCID 8028—
Product5-phenyl-penta-2,4-dienoic acid-N-(2-carboxy-4-fluoro-phenyl)-amideHCID 73993622—

Reaction Steps

Prepared analogously to Example 31 from 5-phenyl-penta-2,4-dienoic acid chloride and 2-amino-5-fluoro-benzoic acid in tetrahydrofuran with the addition of triethylamine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06727250B2
Source datasetuspto-grants-2004_04
ORD IDord-e91f6339cb224f56a0981c95b8f9ef7e
Source noteuspto-grants-2004_04