Sodium Hydroxide → HCID 22724720, compound

HRID 2086575Notes

Reaction equation

HRID 2086575 reaction equation
C[O:2][C:3]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[NH:11][C:12](=[O:26])/[CH:13]=[CH:14]/[C:15]1[CH:24]=[CH:23][C:22]2[C:17](=[CH:18][CH:19]=[C:20]([F:25])[CH:21]=2)[CH:16]=1)=[O:4].[OH-].[Na+]>CO>[C:3]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[NH:11][C:12](=[O:26])/[CH:13]=[CH:14]/[C:15]1[CH:24]=[CH:23][C:22]2[C:17](=[CH:18][CH:19]=[C:20]([F:25])[CH:21]=2)[CH:16]=1)([OH:4])=[O:2]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 22724934HCID 22724934, compound

Product 1

HCID 22724720HCID 22724720, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Prepared analogously to Example 2 from trans-3-(6-fluoro-naphth-2-yl)-acrylic acid-N-(2-methoxycarbonyl-phenyl)-amide and sodium hydroxide solution in methanol.

Sources & evidence

ORD record
ord-e7648296e4784d7eafee3ed9cf797cee
Source dataset
uspto-grants-2004_04
Patent number
US06727250B2

Reaction notes

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