Piperazine → HCID 22725085, compound

Participants

Reaction Conditions

Reaction Steps

Add piperazine (20 mg, 0.23 mmol) to a solution of the product of Step 2 (25 mg, 0.05 mmol) in EtOH (4 ml) at RT. Stir the reaction mixture at 80° C. overnight. Extract and purify to produce the title compound (20 mg). 1H NMR (CDCl3) δ8.24 (d, 1H), 7.93 (d, 2H), 7.26 (d, 2H), 7.22 (t, 2H), 7.10 (t, 2H), 6.33 (d, 1H), 5.64 (s, 1H), 3.67 (s, br, 4H), 3.15 (s, br, 2H), 2.95 (m, 4H), 2.59 (dd, 2H), 2.34 (m, 2H), 2.17 (m, 2H), 1.57 (d, br, 2H).

Provenance & Evidence