HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → HCID 22725079, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | HCID 22725084 | HCID 22725084 | — |
| Catalyst | Lindlars catalyst | HCID 131709914 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 22725079 | HCID 22725079 | — |
Reaction Steps
Add Lindlar catalyst (44 mg) to a suspension of the product from Step 5 (279 mg) in a mixture of EtOAc and CH3OH in the presence of 7N NH3 in CH3OH (1 ml). Hydrogenate the mixture at 1 atm for 1.5 h, filter through celite, wash with NH3/CH3OH (3.5 N) and concentrate to give the desired compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06727254B2 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-d30703a3fcc14e6eb86433155ffeec4d |
| Source note | uspto-grants-2004_04 |