HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triphenylphosphine → [(4-Nitrophenyl)methyl](triphenyl)phosphanium bromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triphenylphosphine | HCID 11776 | — |
| Reactant | 4-Nitrobenzyl bromide | HCID 66011 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | [(4-Nitrophenyl)methyl](triphenyl)phosphanium bromide | HCID 197008 | 115.5% |
Reaction Steps
To a solution of triphenylphosphine (25.92 g) in 300 mL CH2Cl2 is added 4-nitrobenzylbromide (31.47 g). The solution is allowed to stir overnight. The mixture is concentrated. The resulting solid is triturated with Et2O, filtered and dried to yield 54.58 g (95%) of the desired product as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06727248B2 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-eefe74aed8d142559a37515da233ca70 |
| Source note | uspto-grants-2004_04 |