Thiophene-3-boronic acid → HCID 22316667, compound

HRID 2086624Notes

Reaction equation

HRID 2086624 reaction equation
[CH3:1][S:2]([C:5]1[CH:10]=[CH:9][C:8]([N:11]2[C:15]([C:16]3[CH:21]=[CH:20][C:19](Br)=[CH:18][CH:17]=3)=[CH:14][C:13]([C:23]([F:26])([F:25])[F:24])=[N:12]2)=[CH:7][CH:6]=1)(=[O:4])=[O:3].[O:27]1[CH:31]=[CH:30][C:29](B(O)O)=[CH:28]1.S1C=CC(B(O)O)=C1>>[CH3:1][S:2]([C:5]1[CH:10]=[CH:9][C:8]([N:11]2[C:15]([C:16]3[CH:21]=[CH:20][C:19]([C:29]4[CH:30]=[CH:31][O:27][CH:28]=4)=[CH:18][CH:17]=3)=[CH:14][C:13]([C:23]([F:26])([F:25])[F:24])=[N:12]2)=[CH:7][CH:6]=1)(=[O:4])=[O:3]

Participants

4

Reactant 3

HCID 581760Thiophene-3-boronic acidHCID 2734358Furan-3-boronic acidHCID 15340994HCID 15340994, compound

Product 1

HCID 22316667HCID 22316667, compound

Procedure

The title compound was prepared according to the procedure of Example 17 using 1-[4-(Methylsulfonyl)phenyl]-5-(4-bromophenyl)-3-trifluoromethyl-1H-pyrazole and furan-3-boronic acid, instead of thiophen-3-boronic acid.

Sources & evidence

ORD record
ord-290efebd9f8b4b52ac75e553ea85107c
Source dataset
uspto-grants-2004_04
Patent number
US06727238B2

Reaction notes

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