Furan-3-boronic acid → HCID 22316596, compound

HRID 2086640Notes

Reaction equation

HRID 2086640 reaction equation
Br[C:2]1[CH:7]=[CH:6][C:5]([N:8]2[C:12]([C:13]3[CH:18]=[CH:17][C:16]([S:19]([CH3:22])(=[O:21])=[O:20])=[CH:15][CH:14]=3)=[CH:11][CH:10]=[C:9]2[CH3:23])=[CH:4][C:3]=1[CH3:24].[O:25]1[CH:29]=[CH:28][C:27](B(O)O)=[CH:26]1>>[O:25]1[CH:29]=[CH:28][C:27]([C:2]2[CH:7]=[CH:6][C:5]([N:8]3[C:12]([C:13]4[CH:18]=[CH:17][C:16]([S:19]([CH3:22])(=[O:21])=[O:20])=[CH:15][CH:14]=4)=[CH:11][CH:10]=[C:9]3[CH3:23])=[CH:4][C:3]=2[CH3:24])=[CH:26]1

Participants

3

Reactant 2

HCID 2734358Furan-3-boronic acidHCID 22316749HCID 22316749, compound

Product 1

HCID 22316596HCID 22316596, compound

Procedure

The title compound was prepared according to the procedure of Example 35 using 1-(4-bromo-3-methylphenyl)-2-methyl-5-[4-(methylsulfonyl)phenyl]-1H-pyrrole instead of 1-(4-bromophenyl)-2-[3-fluoro-4-(methylsulfonyl)phenyl]-5-methyl-1H-pyrrole and 3-furanboronic acid instead of 2-furanboronic acid in step 4.

Sources & evidence

ORD record
ord-f66713292c0144c09d152c76384a2074
Source dataset
uspto-grants-2004_04
Patent number
US06727238B2

Reaction notes

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