Furan-2-boronic acid → HCID 22316991, compound

HRID 2086702Notes

Reaction equation

HRID 2086702 reaction equation
Br[C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:12]([C:13]3[CH:18]=[CH:17][C:16]([S:19]([CH3:22])(=[O:21])=[O:20])=[C:15]([F:23])[CH:14]=3)[N:11]=[CH:10][CH:9]=2)=[CH:4][CH:3]=1.[O:24]1[CH:28]=[CH:27][CH:26]=[C:25]1B(O)O>>[F:23][C:15]1[CH:14]=[C:13]([N:12]2[C:8]([C:5]3[CH:6]=[CH:7][C:2]([C:25]4[O:24][CH:28]=[CH:27][CH:26]=4)=[CH:3][CH:4]=3)=[CH:9][CH:10]=[N:11]2)[CH:18]=[CH:17][C:16]=1[S:19]([CH3:22])(=[O:21])=[O:20]

Participants

3

Reactant 2

HCID 2734357Furan-2-boronic acidHCID 22316636HCID 22316636, compound

Product 1

HCID 22316991HCID 22316991, compound

Procedure

The title compound was prepared according to the procedure of Example 5 using 5-(4-bromophenyl)-1-[3-fluoro-4-(methylsulfonyl)phenyl]-1H-pyrazole instead of 4-[5-(4-bromophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-1-phenylsulfonamide, 2-furanboronic acid instead of 3-thienylboronic acid.

Sources & evidence

ORD record
ord-ecb1089de9ac44dcb0bfa7007ac91e94
Source dataset
uspto-grants-2004_04
Patent number
US06727238B2

Reaction notes

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