3-Fluorobenzyl bromide → 1-(4-Bromophenyl)-2-(3-fluorophenyl)ethan-1-one

HRID 2086720Notes

Reaction equation

HRID 2086720 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][CH:9]=1)[CH2:5]Br.[Br:10][C:11]1[CH:19]=[CH:18][C:14]([C:15](Cl)=[O:16])=[CH:13][CH:12]=1>>[Br:10][C:11]1[CH:19]=[CH:18][C:14]([C:15](=[O:16])[CH2:5][C:4]2[CH:7]=[CH:8][CH:9]=[C:2]([F:1])[CH:3]=2)=[CH:13][CH:12]=1

Participants

3

Reactant 2

HCID 680073-Fluorobenzyl bromideHCID 685154-Bromobenzoyl chloride

Product 1

HCID 179234721-(4-Bromophenyl)-2-(3-fluorophenyl)ethan-1-one

Procedure

The title compound was prepared according to the procedure of step 1 in the Example 169 using 3-fluorobenzyl bromide and 4-bromobenzoyl chloride.

Sources & evidence

ORD record
ord-a8dc8d48e83b4abeb6d394719ec275e0
Source dataset
uspto-grants-2004_04
Patent number
US06727238B2

Reaction notes

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