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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 208678Generated: October 27, 2026

Water → 3-fluoro-N-[4-chloro-2-hydroxy-5-trifluoromethylphenyl]isonicotinamide

https://huagongshe.com/reaction/208678

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantPyridineHCID 1049—
Reactant3-Fluoropyridine-4-carboxylic acidHCID 345361—
Reactant2-Amino-5-chloro-4-(trifluoromethyl)phenolHCID 14011736—
Product3-fluoro-N-[4-chloro-2-hydroxy-5-trifluoromethylphenyl]isonicotinamideHCID 66880048—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-b8604050eda745e0a59cb30c9418405e
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)