HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 2-[3-(2-Naphthyl)phenylamino]-3-nitropyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-Chloro-3-nitropyridine | HCID 79613 | — |
| Reactant | 2-(3-Aminophenyl)naphthalene | HCID 2760167 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 2-[3-(2-Naphthyl)phenylamino]-3-nitropyridine | HCID 22724445 | 67.2% |
Reaction Steps
A mixture of 3-(2-naphthyl)aniline (5.0 g), 2-chloro-3-nitropyridine (3.62 g) and potassium carbonate (6.31 g) in dioxane (50 ml) was stirred under reflux for 6 days. The reaction mixture was extracted with chloroform and evaporated. Crude residue was chromatographed on silica gel to give 2-[3-(2-naphthyl)phenylamino]-3-nitropyridine as an orange crystal (5.23 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06727245B2 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-0587f41f17724b97b166404a1c09e2d9 |
| Source note | uspto-grants-2004_04 |