HCID 22724068, compound → HCID 22724011, compound

HRID 2086810Notes

Reaction equation

HRID 2086810 reaction equation
[N+:1]([C:4]1[C:5]([NH:10][C:11]2[CH:16]=[CH:15][CH:14]=[C:13]([N:17]3[C:21](=[O:22])[CH2:20][CH2:19][C:18]3=[O:23])[CH:12]=2)=[N:6][CH:7]=[CH:8][CH:9]=1)([O-])=O>[Pd]>[NH2:1][C:4]1[C:5]([NH:10][C:11]2[CH:16]=[CH:15][CH:14]=[C:13]([N:17]3[C:21](=[O:22])[CH2:20][CH2:19][C:18]3=[O:23])[CH:12]=2)=[N:6][CH:7]=[CH:8][CH:9]=1

Participants

3

Reactant 1

HCID 22724068HCID 22724068, compound

Product 1

HCID 22724011HCID 22724011, compoundYield 92.1%

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

The solution of 3-nitro-2-(3-succinimidophenylamino)pyridine (3.47 g) was hydrogenated with palladium on carbon (0.5 g) at 3 atm for 5 hours. The mixture was filtrated and evaporated to give 3-amino-2-(3-succinimidophenylamino)pyridine (2.89 g).

Workup

  1. filtrationThe mixture was filtrated
  2. customevaporated

Sources & evidence

ORD record
ord-c33c3703b02349da829f9c9637223e92
Source dataset
uspto-grants-2004_04
Patent number
US06727245B2

Reaction notes

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