HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 15372233, compound → HCID 22724287, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 15372233 | HCID 15372233 | — |
| Reactant | HCID 22724440 | HCID 22724440 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 22724287 | HCID 22724287 | — |
Reaction Steps
A mixture of 2-[3-(2-naphthyl)phenylamino]-3-aminopyridine and 3-(3-pyridyl)pyruvic acid in ethanol was stirred under reflux for 40 hours. After evaporation of the solvent, crude residue was chromatographed on silica gel to give 4-[3-(2-naphthyl)phenyl]-2-(3-pyridylmethyl)-3-oxo-3,4-dihydropyrido[2,3-b]pyrazine. Crystallization from ether and recrystallization with methanol afforded colorless crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06727245B2 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-c0a89dff8e174501b80f12e9460981ed |
| Source note | uspto-grants-2004_04 |