HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenylpyruvic acid → HCID 22724395, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenylpyruvic acid | HCID 997 | — |
| Reactant | HCID 22723990 | HCID 22723990 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 22724395 | HCID 22724395 | 71.6% |
Reaction Steps
A mixture of 3-amino-2-[3-methoxycarbonyl-5-(2-naphthoylamino)phenylamino]pyridine (180 mg) and 3-phenylpyruvic acid (86 mg) in methanol (4 ml) was stirred under reflux for 4 hours. The precipitate was collected and washed with methanol to give 2-benzyl-4-[3-methoxycarbonyl-5-(2-naphthoylamino)phenyl]-3-oxo-3,4-dihydropyrido[2,3-b]pyrazine (169 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06727245B2 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-c87c7f012c2b41cf8ed585ab5e5e8f23 |
| Source note | uspto-grants-2004_04 |