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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2086982Generated: October 31, 2026

4-(Phenylsulfonyl)aniline → 6-Chloro-4-(4-phenylsulphonylanilino)pyrido[3,4-d]pyrimidine

https://huagongshe.com/reaction/2086982

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Phenylsulfonyl)anilineHCID 516666—
Reactant4,6-Dichloropyrido[3,4-d]pyrimidineHCID 10821876—
Product6-Chloro-4-(4-phenylsulphonylanilino)pyrido[3,4-d]pyrimidineHCID 21952165—

Reaction Steps

Prepared according to Procedure A from 4-benzenesulphonylaniline (Helv. Chim. Acta., 1983, 66 (4), 1046) and 4,6-dichloropyrido[3,4-d]pyrimidine; δH [2H6]-DMSO 9.09 (1H,s), 8.80-8.88 (2H,m), 8.19 (2H,d), 7.94-8.09 (4H,m), 7.53-7.20 (3H,m); m/z (M+1)+ 397.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06727256B1
Source datasetuspto-grants-2004_04
ORD IDord-918af3ea2ffb41a5801855fae9ead98e
Source noteuspto-grants-2004_04