Triethylamine → HCID 11157507, compound

Participants

Reaction Steps

To a mixture of 0.042 g (0.090 mmol) of 17, 0.016 g (0.11 mmol) of t-butyldimethylsilyl chloride, and 0.003 g (0.010 mmol) of DMAP in 2 mL of dichloromethane under argon at 25° C. was added 0.05 mL (0.260 mmol) of triethylamine. The reaction mixture was stirred for 3 h, diluted with 30 mL of water, and extracted three times with diethyl ether (30 mL each). The combined ether extracts were with 30 mL of brine, dried (MgSO4), and concentrated to give 0.051 g (99% yield) of 4.

Provenance & Evidence