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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2087245Generated: October 31, 2026

Propionyl chloride → N-[4-(4-Piperidinyl)phenyl]propanamide

https://huagongshe.com/reaction/2087245

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPropionyl chlorideHCID 62324—
Reactanttert-Butyl 4-(4-aminophenyl)piperidine-1-carboxylateHCID 21940085—
Reactant2-methyl-N-[4-(4-piperidinyl)phenyl]propanamideHCID 21957258—
ProductN-[4-(4-Piperidinyl)phenyl]propanamideHCID 15342128—

Reaction Steps

Prepared by the procedure for 2-methyl-N-[4-(4-piperidinyl)phenyl]propanamide using tert-butyl 4-(4-aminophenyl)-1-piperidinecarboxylate and propanoyl chloride: ESMS m/e: 233.1 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06727264B1
Source datasetuspto-grants-2004_04
ORD IDord-792212126f43438f88e9c41419189372
Source noteuspto-grants-2004_04