HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclopropanecarbonyl chloride → N-[3-(4-Piperidinyl)phenyl]cyclopropanecarboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclopropanecarbonyl chloride | HCID 77637 | — |
| Reactant | 2-methyl-N-[4-(4-piperidinyl)phenyl]propanamide | HCID 21957258 | — |
| Reactant | tert-Butyl 4-(3-aminophenyl)piperidine-1-carboxylate | HCID 22049268 | — |
| Product | N-[3-(4-Piperidinyl)phenyl]cyclopropanecarboxamide | HCID 22048669 | — |
Reaction Steps
Prepared by the procedure for 2-methyl-N-[4-(4-piperidinyl)phenyl]propanamide using tert-butyl 4-(3-aminophenyl)-1-piperidinecarboxylate and cyclopropanecarbonyl chloride: Anal. Calcd for C15H20N2O+0.15CH2Cl2: C, 70.8; H, 7.87; N, 10.9. found: C, 70.9; H, 7.68; N, 11.1; ESMS m/e: 245.0 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06727264B1 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-db5a85ca8459435e920770f003a62522 |
| Source note | uspto-grants-2004_04 |