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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2087248Generated: October 31, 2026

Propionyl chloride → N-[3-(4-Piperidinyl)phenyl]propanamide

https://huagongshe.com/reaction/2087248

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPropionyl chlorideHCID 62324—
Reactant2-methyl-N-[4-(4-piperidinyl)phenyl]propanamideHCID 21957258—
Reactanttert-Butyl 4-(3-aminophenyl)piperidine-1-carboxylateHCID 22049268—
ProductN-[3-(4-Piperidinyl)phenyl]propanamideHCID 22048836—

Reaction Steps

Prepared by the procedure for 2-methyl-N-[4-(4-piperidinyl)phenyl]propanamide using tert-butyl 4-(3-aminophenyl)-1-piperidinecarboxylate and propanoyl chloride: Anal. Calcd for C14H20N2O: C, 72.2; H, 8.63; N, 12.1. found: C, 72.4; H, 8.68; N, 12.1; ESMS m/e: 233.1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06727264B1
Source datasetuspto-grants-2004_04
ORD IDord-e1d945a5c4eb4251a751bff29077b667
Source noteuspto-grants-2004_04