2,5-Dimethyl-1-[3-(trifluoromethyl)phenyl]-1H-pyrrole-3-carbaldehyde → HCID 22049406, compound

HRID 2087343Notes

Reaction equation

HRID 2087343 reaction equation
[CH3:1][C:2]1[N:3]([C:10]2[CH:15]=[CH:14][CH:13]=[C:12]([C:16]([F:19])([F:18])[F:17])[CH:11]=2)[C:4]([CH3:9])=[CH:5][C:6]=1[CH:7]=O.[CH3:20][CH:21]([CH3:37])[C:22]([NH:24][C:25]1[CH:30]=[CH:29][CH:28]=[C:27]([CH:31]2[CH2:36][CH2:35][NH:34][CH2:33][CH2:32]2)[CH:26]=1)=[O:23]>>[CH3:1][C:2]1[N:3]([C:10]2[CH:15]=[CH:14][CH:13]=[C:12]([C:16]([F:18])([F:17])[F:19])[CH:11]=2)[C:4]([CH3:9])=[CH:5][C:6]=1[CH2:7][N:34]1[CH2:35][CH2:36][CH:31]([C:27]2[CH:26]=[C:25]([NH:24][C:22](=[O:23])[CH:21]([CH3:37])[CH3:20])[CH:30]=[CH:29][CH:28]=2)[CH2:32][CH2:33]1

Participants

3

Reactant 2

HCID 6223762,5-Dimethyl-1-[3-(trifluoromethyl)phenyl]-1H-pyrrole-3-carbaldehydeHCID 167572552-methyl-N-[3-(4-piperidyl)phenyl]propanamide

Product 1

HCID 22049406HCID 22049406, compound

Procedure

Prepared by Procedure F and Scheme R using 2,5-dimethyl-1-[3-(trifluoromethyl)phenyl]-1H-pyrrole-3-carbaldehyde and 2-methyl-N-[3-(4-piperidinyl)phenyl]propanamide: ESMS m/e: 498.2 (M+H)+.

Workup

  1. customPrepared by Procedure F and Scheme R

Sources & evidence

ORD record
ord-c1dc98fc692d42629af5896b2a8be0eb
Source dataset
uspto-grants-2004_04
Patent number
US06727264B1

Reaction notes

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