3-(4-Chlorophenoxy)benzaldehyde → N-(3-{1-[3-(4-Chlorophenoxy)benzyl]-4-piperidinyl}phenyl)-2-methylpropanamide

HRID 2087352Notes

Reaction equation

HRID 2087352 reaction equation
[Cl:1][C:2]1[CH:16]=[CH:15][C:5]([O:6][C:7]2[CH:8]=[C:9]([CH:12]=[CH:13][CH:14]=2)[CH:10]=O)=[CH:4][CH:3]=1.[CH3:17][CH:18]([CH3:34])[C:19]([NH:21][C:22]1[CH:27]=[CH:26][CH:25]=[C:24]([CH:28]2[CH2:33][CH2:32][NH:31][CH2:30][CH2:29]2)[CH:23]=1)=[O:20]>>[Cl:1][C:2]1[CH:16]=[CH:15][C:5]([O:6][C:7]2[CH:8]=[C:9]([CH:12]=[CH:13][CH:14]=2)[CH2:10][N:31]2[CH2:32][CH2:33][CH:28]([C:24]3[CH:23]=[C:22]([NH:21][C:19](=[O:20])[CH:18]([CH3:17])[CH3:34])[CH:27]=[CH:26][CH:25]=3)[CH2:29][CH2:30]2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 6160153-(4-Chlorophenoxy)benzaldehydeHCID 167572552-methyl-N-[3-(4-piperidyl)phenyl]propanamide

Product 1

HCID 16756637N-(3-{1-[3-(4-Chlorophenoxy)benzyl]-4-piperidinyl}phenyl)-2-methylpropanamide

Procedure

Prepared by Procedure F and Scheme R using 3-(4-chlorophenoxy)benzaldehyde and 2-methyl-N-[3-(4-piperidinyl)phenyl]propanamide: ESMS m/e: 463.2 (M+H)+.

Workup

  1. customPrepared by Procedure F and Scheme R

Sources & evidence

ORD record
ord-bbcdec26a5154ce2bbf3fcb0c9ec65c3
Source dataset
uspto-grants-2004_04
Patent number
US06727264B1

Reaction notes

Loading…