3,4-Dimethylthieno[2,3-B]Thiophene-2-Carbaldehyde → N-(3-{1-[(3,4-Dimethylthieno[2,3-B]thien-2-YL)methyl]-4-piperidinyl}phenyl)-2-methylpropanamide

HRID 2087357Notes

Reaction equation

HRID 2087357 reaction equation
[CH3:1][C:2]1[C:9]2[C:8]([CH3:10])=[CH:7][S:6][C:5]=2[S:4][C:3]=1[CH:11]=O.[CH3:13][CH:14]([CH3:30])[C:15]([NH:17][C:18]1[CH:23]=[CH:22][CH:21]=[C:20]([CH:24]2[CH2:29][CH2:28][NH:27][CH2:26][CH2:25]2)[CH:19]=1)=[O:16]>>[CH3:1][C:2]1[C:9]2[C:8]([CH3:10])=[CH:7][S:6][C:5]=2[S:4][C:3]=1[CH2:11][N:27]1[CH2:28][CH2:29][CH:24]([C:20]2[CH:19]=[C:18]([NH:17][C:15](=[O:16])[CH:14]([CH3:13])[CH3:30])[CH:23]=[CH:22][CH:21]=2)[CH2:25][CH2:26]1

Participants

3

Reactant 2

HCID 27787713,4-Dimethylthieno[2,3-B]Thiophene-2-CarbaldehydeHCID 167572552-methyl-N-[3-(4-piperidyl)phenyl]propanamide

Product 1

HCID 22048896N-(3-{1-[(3,4-Dimethylthieno[2,3-B]thien-2-YL)methyl]-4-piperidinyl}phenyl)-2-methylpropanamide

Procedure

Prepared by Procedure F and Scheme R using 3,4-dimethylthieno[2,3-b]thiophene-2-carbaldehyde and 2-methyl-N-[3-(4-piperidinyl)phenyl]propanamide: ESMS m/e: 427.1 (M+H)+.

Workup

  1. customPrepared by Procedure F and Scheme R

Sources & evidence

ORD record
ord-5c8a09c876e64efea8ab7aebd04690cc
Source dataset
uspto-grants-2004_04
Patent number
US06727264B1

Reaction notes

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