2-methyl-N-[3-(4-piperidyl)phenyl]propanamide → HCID 178454455, compound

HRID 2087358Notes

Reaction equation

HRID 2087358 reaction equation
[F:1][C:2]([F:17])([F:16])[C:3]1[CH:8]=[CH:7][C:6]([C:9]2[C:13]([CH:14]=O)=[CH:12][NH:11][N:10]=2)=[CH:5][CH:4]=1.[CH3:18][CH:19]([CH3:35])[C:20]([NH:22][C:23]1[CH:28]=[CH:27][CH:26]=[C:25]([CH:29]2[CH2:34][CH2:33][NH:32][CH2:31][CH2:30]2)[CH:24]=1)=[O:21]>>[CH3:18][CH:19]([CH3:35])[C:20]([NH:22][C:23]1[CH:28]=[CH:27][CH:26]=[C:25]([CH:29]2[CH2:34][CH2:33][N:32]([CH2:14][C:13]3[C:9]([C:6]4[CH:7]=[CH:8][C:3]([C:2]([F:17])([F:16])[F:1])=[CH:4][CH:5]=4)=[N:10][NH:11][CH:12]=3)[CH2:31][CH2:30]2)[CH:24]=1)=[O:21]

Participants

3

Reactant 2

HCID 167572552-methyl-N-[3-(4-piperidyl)phenyl]propanamideHCID 178519877HCID 178519877, compound

Product 1

HCID 178454455HCID 178454455, compound

Procedure

Prepared by Procedure F and Scheme R using 3-[4-(trifluoromethyl)phenyl]-1H-pyrazole-4-carbaldehyde and 2-methyl-N-[3-(4-piperidinyl)phenyl]propanamide: ESMS m/e: 471.1 (M+H)+.

Workup

  1. customPrepared by Procedure F and Scheme R

Sources & evidence

ORD record
ord-ea3af02ec36b4c93844cb08542e28eac
Source dataset
uspto-grants-2004_04
Patent number
US06727264B1

Reaction notes

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