Ethyl 4-Formyl-2,5-Dimethyl-1-Phenyl-1H-Pyrrole-3-Carboxylate → HCID 22049090, compound
Reaction equation
[CH:1]([C:3]1[C:4]([C:16]([O:18][CH2:19][CH3:20])=[O:17])=[C:5]([CH3:15])[N:6]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[C:7]=1[CH3:8])=O.[CH3:21][CH:22]([CH3:38])[C:23]([NH:25][C:26]1[CH:31]=[CH:30][CH:29]=[C:28]([CH:32]2[CH2:37][CH2:36][NH:35][CH2:34][CH2:33]2)[CH:27]=1)=[O:24]>>[C:23]([NH:25][C:26]1[CH:27]=[C:28]([CH:32]2[CH2:33][CH2:34][N:35]([CH2:1][C:3]3[C:4]([C:16]([O:18][CH2:19][CH3:20])=[O:17])=[C:5]([CH3:15])[N:6]([C:9]4[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=4)[C:7]=3[CH3:8])[CH2:36][CH2:37]2)[CH:29]=[CH:30][CH:31]=1)(=[O:24])[CH:22]([CH3:38])[CH3:21]Participants
3
Procedure
Prepared by Procedure F and Scheme R using ethyl 4-formyl-2,5-dimethyl-1-phenyl-1H-pyrrole-3-carboxylate and 2-methyl-N-[3-(4-piperidinyl)phenyl]propanamide: ESMS m/e: 502.2 (M+H)+.
Workup
- customPrepared by Procedure F and Scheme R
Sources & evidence
- ORD record
- ord-bfa7d35647e04dbc8250d8a2c2e187b5
- Source dataset
- uspto-grants-2004_04
- Patent number
- US06727264B1
Reaction notes
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