5-Phenylthiophene-2-carbaldehyde → HCID 178454453, compound

HRID 2087375Notes

Reaction equation

HRID 2087375 reaction equation
C1([C:7]2[S:11][C:10]([CH:12]=O)=[CH:9][CH:8]=2)C=CC=CC=1.[CH3:14][CH:15]([CH3:31])[C:16]([NH:18][C:19]1[CH:24]=[CH:23][CH:22]=[C:21]([CH:25]2[CH2:30][CH2:29][NH:28][CH2:27][CH2:26]2)[CH:20]=1)=[O:17]>>[CH3:14][CH:15]([CH3:31])[C:16]([NH:18][C:19]1[CH:24]=[CH:23][CH:22]=[C:21]([CH:25]2[CH2:30][CH2:29][N:28]([CH2:12][C:10]3[SH:11]([C:19]4[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=4)[CH:7]=[CH:8][CH:9]=3)[CH2:27][CH2:26]2)[CH:20]=1)=[O:17]

Participants

3

Reactant 2

HCID 1770535-Phenylthiophene-2-carbaldehydeHCID 167572552-methyl-N-[3-(4-piperidyl)phenyl]propanamide

Product 1

HCID 178454453HCID 178454453, compound

Procedure

Prepared by Procedure F and Scheme R using 5-phenyl-2-thiophenecarbaldehyde and 2-methyl-N-[3-(4-piperidinyl)phenyl]propanamide: ESMS m/e: 419.1 (M+H)+.

Workup

  1. customPrepared by Procedure F and Scheme R

Sources & evidence

ORD record
ord-c9555c4fd77c4702943ed44d1c37c1b6
Source dataset
uspto-grants-2004_04
Patent number
US06727264B1

Reaction notes

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