4-(1H-imidazol-1-yl)benzaldehyde → HCID 22048717, compound
Reaction equation
[N:1]1([C:6]2[CH:13]=[CH:12][C:9]([CH:10]=O)=[CH:8][CH:7]=2)[CH:5]=[CH:4][N:3]=[CH:2]1.[CH3:14][CH:15]([CH3:31])[C:16]([NH:18][C:19]1[CH:24]=[CH:23][CH:22]=[C:21]([CH:25]2[CH2:30][CH2:29][NH:28][CH2:27][CH2:26]2)[CH:20]=1)=[O:17]>>[N:1]1([C:6]2[CH:13]=[CH:12][C:9]([CH2:10][N:28]3[CH2:29][CH2:30][CH:25]([C:21]4[CH:20]=[C:19]([NH:18][C:16](=[O:17])[CH:15]([CH3:14])[CH3:31])[CH:24]=[CH:23][CH:22]=4)[CH2:26][CH2:27]3)=[CH:8][CH:7]=2)[CH:5]=[CH:4][N:3]=[CH:2]1Participants
3
Procedure
Prepared by Procedure F and Scheme R using 4-(1H-imidazol-1-yl)benzaldehyde and 2-methyl-N-[3-(4-piperidinyl)phenyl]propanamide: ESMS m/e: 403.2 (M+H)+.
Workup
- customPrepared by Procedure F and Scheme R
Sources & evidence
- ORD record
- ord-c96cf98ebc234c5fba4ac5843f5bf2dd
- Source dataset
- uspto-grants-2004_04
- Patent number
- US06727264B1
Reaction notes
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