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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2087416Generated: October 26, 2026

Tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,3,6-tetrahydropyridine-1-carboxylate → Tert-butyl 4-[3-(isobutyrylamino)-4-methylphenyl]-3,6-dihydro-1(2H)-pyridinecarboxylate

https://huagongshe.com/reaction/2087416

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,3,6-tetrahydropyridine-1-carboxylateHCID 4642098—
ReactantN-(5-bromo-2-methylphenyl)-2-methylpropanamideHCID 22048850—
ProductTert-butyl 4-[3-(isobutyrylamino)-4-methylphenyl]-3,6-dihydro-1(2H)-pyridinecarboxylateHCID 22049498—

Reaction Steps

Prepared by Procedure W and Scheme AF using N-(5-bromo-2-methylphenyl)-2-methylpropanamide and tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydro-1(2H)-pyridinecarboxylate: ESMS m/e: 259.1 (M - 100)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06727264B1
Source datasetuspto-grants-2004_04
ORD IDord-28d192dbbe5749c1981e71eea8e247ad
Source noteuspto-grants-2004_04