9-ethyl-9H-carbazole-3-carbaldehyde → N-(5-{1-[(9-Ethyl-9H-carbazol-3-YL)methyl]-4-piperidinyl}-2-methylphenyl)-2-methylpropanamide

HRID 2087417Notes

Reaction equation

HRID 2087417 reaction equation
[CH2:1]([N:3]1[C:15]2[CH:14]=[CH:13][C:12]([CH:16]=O)=[CH:11][C:10]=2[C:9]2[C:4]1=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH3:2].[CH3:18][CH:19]([CH3:36])[C:20]([NH:22][C:23]1[CH:28]=[C:27]([CH:29]2[CH2:34][CH2:33][NH:32][CH2:31][CH2:30]2)[CH:26]=[CH:25][C:24]=1[CH3:35])=[O:21]>>[CH2:1]([N:3]1[C:15]2[CH:14]=[CH:13][C:12]([CH2:16][N:32]3[CH2:33][CH2:34][CH:29]([C:27]4[CH:26]=[CH:25][C:24]([CH3:35])=[C:23]([NH:22][C:20](=[O:21])[CH:19]([CH3:36])[CH3:18])[CH:28]=4)[CH2:30][CH2:31]3)=[CH:11][C:10]=2[C:9]2[C:4]1=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH3:2]

Participants

3

Reactant 2

HCID 820559-ethyl-9H-carbazole-3-carbaldehydeHCID 220486082-methyl-N-[2-methyl-5-(4-piperidinyl)phenyl]propanamide

Product 1

HCID 22049006N-(5-{1-[(9-Ethyl-9H-carbazol-3-YL)methyl]-4-piperidinyl}-2-methylphenyl)-2-methylpropanamide

Procedure

Prepared by Procedure AA and Scheme AJ using 9-ethyl-9H-carbazole-3-carbaldehyde and 2-methyl-N-[2-methyl-5-(4-piperidinyl)phenyl]propanamide: ESMS m/e: 468.1 (M+H)+.

Workup

  1. customPrepared by Procedure AA and Scheme AJ

Sources & evidence

ORD record
ord-b5f77c29fc824927bcf0a875e554c4ce
Source dataset
uspto-grants-2004_04
Patent number
US06727264B1

Reaction notes

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