HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(2,6-Dichlorophenyl)-5-methylisoxazole-4-carbonyl chloride → (1S)-3-{4-[3-(Isobutyrylamino)phenyl]-1-piperidinyl}-1-phenylpropyl 3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolecarboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(2,6-Dichlorophenyl)-5-methylisoxazole-4-carbonyl chloride | HCID 78212 | — |
| Reactant | N-(3-{1-[(3S)-3-Hydroxy-3-Phenylpropyl]-4-Piperidinyl}Phenyl)-2-Methylpropanamide | HCID 60078700 | — |
| Product | (1S)-3-{4-[3-(Isobutyrylamino)phenyl]-1-piperidinyl}-1-phenylpropyl 3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolecarboxylate | HCID 58651314 | — |
Reaction Steps
Prepared by Procedure Q1 and Scheme C2 (TEA) using N-(3-{1-[(3S)-3-hydroxy-3-phenylpropyl]-4-piperidinyl}phenyl)-2-methylpropanamide and 3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolecarbonyl chloride: ESMS m/e: 633.6 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06727264B1 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-97bbf28a2a2e49ff82ca367ce4ca1dc2 |
| Source note | uspto-grants-2004_04 |