HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Isoxazolecarbonyl chloride, 3-(2-chlorophenyl)-5-methyl- → 4-{4-[3-(Isobutyrylamino)phenyl]-1-piperidinyl}butyl 3-(2-chlorophenyl)-5-methyl-4-isoxazolecarboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Isoxazolecarbonyl chloride, 3-(2-chlorophenyl)-5-methyl- | HCID 96590 | — |
| Reactant | N-(3-[1-(4-hydroxybutyl)-4-piperidinyl]phenyl}-2-methylpropanamide | HCID 22048659 | — |
| Product | 4-{4-[3-(Isobutyrylamino)phenyl]-1-piperidinyl}butyl 3-(2-chlorophenyl)-5-methyl-4-isoxazolecarboxylate | HCID 22049383 | — |
Reaction Steps
Prepared by Procedure Q1 and Scheme C2 (TEA) using N-{3-[1-(4-hydroxybutyl)-4-piperidinyl]phenyl}-2-methylpropanamide and 3-(2-chlorophenyl)-5-methyl-4-isoxazolecarbonyl chloride: ESMS m/e: 538.2 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06727264B1 |
| Source dataset | uspto-grants-2004_04 |
| ORD ID | ord-9bf0b474a0e24036970670f3ef1e43be |
| Source note | uspto-grants-2004_04 |