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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2087447Generated: October 25, 2026

3-(2,6-Dichlorophenyl)-5-methylisoxazole-4-carbonyl chloride → 4-{4-[3-(Isobutyrylamino)phenyl]-1-piperidinyl}butyl 3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolecarboxylate

https://huagongshe.com/reaction/2087447

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(2,6-Dichlorophenyl)-5-methylisoxazole-4-carbonyl chlorideHCID 78212—
ReactantN-(3-[1-(4-hydroxybutyl)-4-piperidinyl]phenyl}-2-methylpropanamideHCID 22048659—
Product4-{4-[3-(Isobutyrylamino)phenyl]-1-piperidinyl}butyl 3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolecarboxylateHCID 22049462—

Reaction Steps

Prepared by Procedure Q1 and Scheme C2 (TEA) using N-{3-[1-(4-hydroxybutyl)-4-piperidinyl]phenyl}-2-methylpropanamide and 3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolecarbonyl chloride: ESMS m/e: 572.2 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06727264B1
Source datasetuspto-grants-2004_04
ORD IDord-d532421ad2314f389d2a6d98743d5c49
Source noteuspto-grants-2004_04