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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2087457Generated: November 1, 2026

3,5-Dichlorobenzoyl chloride → 3,5-Dichloro-N-((1S)-3-{4-[3-(isobutyrylamino)phenyl]-1-piperidinyl}-1-phenylpropyl)benzamide

https://huagongshe.com/reaction/2087457

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,5-Dichlorobenzoyl chlorideHCID 76191—
ReactantN-(3-(1-[(3S)-3-amino-3-phenylpropyl]-4-piperidinyl)phenyl)-2-methylpropanamideHCID 69523474—
Product3,5-Dichloro-N-((1S)-3-{4-[3-(isobutyrylamino)phenyl]-1-piperidinyl}-1-phenylpropyl)benzamideHCID 58651298—

Reaction Steps

Prepared by Procedure Q1 and Scheme AC using N-(3-{1-[(3S)-3-amino-3-phenylpropyl]-4-piperidinyl}phenyl)-2-methylpropanamide and 3,5-dichlorobenzoyl chloride: ESMS m/e: 552.3 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06727264B1
Source datasetuspto-grants-2004_04
ORD IDord-9739a8a4750547229876d7ae5f0a1b4f
Source noteuspto-grants-2004_04