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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2087466Generated: October 25, 2026

2-Phenoxypyridine-3-carbonyl chloride → N-((1S)-3-{4-[3-(Isobutyrylamino)phenyl]-1-piperidinyl}-1-phenylpropyl)-2-phenoxynicotinamide

https://huagongshe.com/reaction/2087466

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Phenoxypyridine-3-carbonyl chlorideHCID 2774306—
ReactantN-(3-(1-[(3S)-3-amino-3-phenylpropyl]-4-piperidinyl)phenyl)-2-methylpropanamideHCID 69523474—
ProductN-((1S)-3-{4-[3-(Isobutyrylamino)phenyl]-1-piperidinyl}-1-phenylpropyl)-2-phenoxynicotinamideHCID 58651339—

Reaction Steps

Prepared by Procedure Q1 and Scheme AC using N-(3-{1-[(3S)-3-amino-3-phenylpropyl]-4-piperidinyl}phenyl)-2-methylpropanamide and 2-phenoxynicotinoyl chloride: ESMS m/e: 577.3 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06727264B1
Source datasetuspto-grants-2004_04
ORD IDord-94b8d8a7bece4e279bffd51bfe69c75e
Source noteuspto-grants-2004_04