HCID 22048862, compound → HCID 58651317, compound

HRID 2087467Notes

Reaction equation

HRID 2087467 reaction equation
[NH2:1][C@H:2]([C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1)[CH2:3][CH2:4][N:5]1[CH2:10][CH2:9][CH:8]([C:11]2[CH:12]=[C:13]([NH:17][C:18](=[O:22])[CH:19]([CH3:21])[CH3:20])[CH:14]=[CH:15][CH:16]=2)[CH2:7][CH2:6]1.[Cl:29][C:30]1[CH:35]=[CH:34][C:33]([N:36]2[CH:40]=[C:39]([C:41](Cl)=[O:42])[C:38]([CH2:44][CH2:45][CH3:46])=[N:37]2)=[CH:32][CH:31]=1>>[Cl:29][C:30]1[CH:31]=[CH:32][C:33]([N:36]2[CH:40]=[C:39]([C:41]([NH:1][C@H:2]([C:23]3[CH:24]=[CH:25][CH:26]=[CH:27][CH:28]=3)[CH2:3][CH2:4][N:5]3[CH2:10][CH2:9][CH:8]([C:11]4[CH:16]=[CH:15][CH:14]=[C:13]([NH:17][C:18](=[O:22])[CH:19]([CH3:21])[CH3:20])[CH:12]=4)[CH2:7][CH2:6]3)=[O:42])[C:38]([CH2:44][CH2:45][CH3:46])=[N:37]2)=[CH:34][CH:35]=1

Participants

3

Reactant 2

HCID 22048862HCID 22048862, compoundHCID 69523474N-(3-(1-[(3S)-3-amino-3-phenylpropyl]-4-piperidinyl)phenyl)-2-methylpropanamide

Product 1

HCID 58651317HCID 58651317, compound

Procedure

Prepared by Procedure Q1 and Scheme AC using N-(3-{1-[(3S)-3-amino-3-phenylpropyl]-4-piperidinyl}phenyl)-2-methylpropanamide and 1-(4-chlorophenyl)-3-propyl-1H-pyrazole-4-carbonyl chloride: ESMS m/e: 626.3 (M+H)+.

Workup

  1. customPrepared by Procedure Q1 and Scheme AC

Sources & evidence

ORD record
ord-b8c7c21852b54e599e03e5f225669615
Source dataset
uspto-grants-2004_04
Patent number
US06727264B1

Reaction notes

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