HCID 22048996, compound → HCID 58651312, compound

HRID 2087472Notes

Reaction equation

HRID 2087472 reaction equation
[NH2:1][C@H:2]([C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1)[CH2:3][CH2:4][N:5]1[CH2:10][CH2:9][CH:8]([C:11]2[CH:12]=[C:13]([NH:17][C:18](=[O:22])[CH:19]([CH3:21])[CH3:20])[CH:14]=[CH:15][CH:16]=2)[CH2:7][CH2:6]1.[C:29]1([N:35]2[CH:39]=[C:38]([C:40](Cl)=[O:41])[C:37]([CH2:43][CH2:44][CH3:45])=[N:36]2)[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=1>>[C:18]([NH:17][C:13]1[CH:12]=[C:11]([CH:8]2[CH2:9][CH2:10][N:5]([CH2:4][CH2:3][C@H:2]([NH:1][C:40]([C:38]3[C:37]([CH2:43][CH2:44][CH3:45])=[N:36][N:35]([C:29]4[CH:30]=[CH:31][CH:32]=[CH:33][CH:34]=4)[CH:39]=3)=[O:41])[C:23]3[CH:24]=[CH:25][CH:26]=[CH:27][CH:28]=3)[CH2:6][CH2:7]2)[CH:16]=[CH:15][CH:14]=1)(=[O:22])[CH:19]([CH3:21])[CH3:20]

Participants

3

Reactant 2

HCID 22048996HCID 22048996, compoundHCID 69523474N-(3-(1-[(3S)-3-amino-3-phenylpropyl]-4-piperidinyl)phenyl)-2-methylpropanamide

Product 1

HCID 58651312HCID 58651312, compound

Procedure

Prepared by Procedure Q1 and Scheme AC using N-(3-{1-[(3S)-3-amino-3-phenylpropyl]-4-piperidinyl}phenyl)-2-methylpropanamide and 1-phenyl-3-propyl-1H-pyrazole-4-carbonyl chloride: ESMS m/e: 592.2 (M+H)+.

Workup

  1. customPrepared by Procedure Q1 and Scheme AC

Sources & evidence

ORD record
ord-ea355ac7e3fe4c32b8e49f97a0d69224
Source dataset
uspto-grants-2004_04
Patent number
US06727264B1

Reaction notes

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