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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2087549Generated: October 29, 2026

2-methyl-N-[3-(4-piperidyl)phenyl]propanamide → N-(3-{1-[(2S)-3-(4-Bromophenoxy)-2-methylpropyl]-4-piperidinyl}phenyl)-2-methylpropanamide

https://huagongshe.com/reaction/2087549

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-methyl-N-[3-(4-piperidyl)phenyl]propanamideHCID 16757255—
Reactant4-bromophenyl(2R)-3-chloro-2-methylpropyl etherHCID 86610999—
ProductN-(3-{1-[(2S)-3-(4-Bromophenoxy)-2-methylpropyl]-4-piperidinyl}phenyl)-2-methylpropanamideHCID 58651344—

Reaction Steps

Prepared by Procedure G and Scheme B1 using 4-bromophenyl(2R)-3-chloro-2-methylpropyl ether and 2-methyl-N-[3-(4-piperidinyl)phenyl]propanamide: ESMS m/e: 473.0 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06727264B1
Source datasetuspto-grants-2004_04
ORD IDord-af9c0d2ac576449fb0e1d870fca3c9c1
Source noteuspto-grants-2004_04